Associate Dean for Academic Affairs
Room 1033W Dental Center, 345 East 24th Street
PostDoc Fellow, Monell Chemical Senses Center, Philadelphia, PA 1989
PhD, Biochemistry/Oral Biology, University of Toronto, Toronto, Canada 1988
MS, University of Toronto, Toronto, Canada 1985
Certificate in Oral Surgery, Technion Institute of Technology, Haifa, Israel 1982
DMD, University of Medicine and Pharmacy, Tirgu Mures, Romania 1974
Dental education is at a crossroads. Health care reform, interdisciplinary education, the digital revolution and the role of dentists in overall health, are all shaping how we teach and test in and outside a dental school. We are interested in innovative ways of delivering curriculum, promoting learning rather than testing, and emphasizing integration and clinical application of basic science concepts.
We are also interested in the peripheral mechanisms of taste transduction, primarily that of the bitter and sour taste. We collect human taste tissue and study taste signal transduction mechanisms monitoring generation of second messengers such as cAMP, IP3 and cGMP that accumulate in taste cells within milliseconds after gustatory stimulation.
Finally, we are interested in the History of Medicine and Dentistry, the role others had played before us in shaping current knowledge which is essential for us to appreciate the present.
Complete listing available on the NYU Health Sciences Library site.
Relevant Publications on Taste
Spielman, A.I., Brand, J.G. (Editors). Experimental Cell Biology of Taste and Olfaction. CRC Press, Boca Raton, FL, pp. 437, 1995.
Huang, L., Shanker, Y.G., Dubauskaite, J., Zheng, J.Z., Yan, W., Rosenzweig, S., Spielman, A.I., et al. Ggamma13, a novel G protein gamma subunit expressed in gustducin-positive taste receptor cells, mediates IP3 responses to bitter denatonium. Nature Neurosci 2(1999): 1055-1062.
Shaul, ME, Malach, E., Peri, I, Huang, L., Spielman, A.I., et al, (2015). Intracellular inhibition of GRK2 activity by membrane-permeant tastants amplifies β2 adrenergic receptor signaling and delays desensitization: Implication for GRK2-dependent Gas signaling of GPCRs. Biochim Biophys. Acta 1850 (7):1375-88.
Lipchock, S.V., Mennella, J.A., Spielman, A.I., Mansfield, C.J., Hwang, L-D, Douglas, J., and Reed D. (2017) Caffeine bitterness is related to daily caffeine intake and bitter receptor mRNA abundance in human taste tissue. Perception, 1:1-12.
Qian J., Mummalaneni, S., Phan, H., Heck, G.L., DeSimone, J., West, D., Mahavadi, S., Murthy, K.S., Rhyu, M.R., Spielman, A.I., et al., (2017) Cyclic-AMP Regulates Postnatal Development of Neural and Behavioral Responses to NaCl in Rats. PLOS One 12(2): e0171335.
Spielman, A.I. (2017). Taste Disorders. In: Clinician's Guide to the Diagnosis and Treatment of Salivary Gland and Chemosensory Disorders, P.Fox Ed. (in press)
Relevant Publications on Education
Spielman, A.I., Fulmer, T., Eisenberg, E., and Alfano, M.C. (2005). Dentistry, Nursing and Medicine: A Comparison of Core Competencies. J Dent Ed, 69:1257-1271.
Lai H., Gierl, M.J., Byrne, E.B., Spielman, A.I., Waldschmidt, D.W. (2016). Three Modeling Applications to Promote Automatic Item Generation for Examinations in Dentistry. J Dent Ed 80, 3, p. 339-347.
Tsai, T.H., Spielman, A.I. and Kramer, G.A. (2017) An overview of the models in reporting school data on dental credentialing examinations. J Dent Ed 81:2 178-189.
Schloss, A.J., Verjee, N., Spielman, A.I. (2017). The Era of Personalized Dentistry Is Upon Us: It's Time to Include It in Dental Curricula (Guest Editorial). J Dent Ed 81:4, 363-365.
Relevant Publications on History of Dentistry
Spielman, A.I. (2007). The Birth of the Most Important 18th Century Dental text: Pierre Fauchard's Le Chirurgien Dentist. J Dent Res, 10: 922-926.
Spielman, A.I. (2009). The Boy with the Golden Tooth - 1595 Case Report about the Use of Gold Foil in Dentistry. J Dent Res 88:8-11.
Seiler, R., Spielman, A.I., Zink, A., and Rühli, F. (2013) The Oral Pathologies of the Neolithic Iceman - ca 3300 BC - European J Oral Sciences, 121:3pt1, June 2013, 137-141.