421 First Avenue, Suite 7W, New York, NY 10010
MAS, Clinical Research, University of California San Francisco 2010
Certificate, Endodontics, University of California San Francisco 2008
PhD, Neuropharmacology, University of Texas Health Science Center San Antonio 2005
DDS, University of Texas Health Science Center San Antonio 2005
BS, Biochemistry, Trinity University 1998
As an endodontist, I regularly observe the tremendous suffering and anxiety experienced by patients experiencing acute dental pain, particularly those with symptomatic pulpitis. As a neuroscientist, I am interested in understanding the molecular signature that impart pulpal afferents with such powerful nociceptive properties. Of great interest are the family of TRP channels, several of which are known to play an important role in the induction of inflammatory and neuropathic pain. Also of interest is the role of afferents in healing, repair, and regenerative processes of the pulp. The primary goal of our translational orofacial pain research group is to approach scientific questions in a manner that will be most likely to directly impact patient care.
Complete listing available on the NYU Health Sciences Library site.
Alobaid AS, Cortex LM, Lo J, Nguyen TT, Albert J, Abu-Melha AS, Lin LM, Gibbs JL. Radiographic and Clinical Outcomes of the Treatment of Immature Permanent Teeth by Revascularization or Apexification: A Pilot Retrospective Cohort Study. Accepted with revisions December 2013.
Flake NM, Gibbs JL*, Diogenes A, Hargreaves KM, Khan AA. A standardized novel method to measure radiographic root changes after endodontic therapy in immature teeth. In Press J. Endod. * Co-first author
Shimizu E, Ricucci D, Albert J, Alobaid AS, Gibbs JL, Huang GT, Lin LM. Clinical, radiographic, and histological observation of a human immature permanent tooth with chronic apical abscess after revitalization treatment. J. Endod. 39(8): 1078-83.
Martin G, Ricucci D, Gibbs JL, Lin LM. Histological findings of revascularized/revitalized immature permanent molar with apical periodontitis using platelet-rich plasma. J.Endod. 39(1): 138-44, 201
Gibbs JL, Urban R, Basbaum AI. Paradoxical surrogate markers of dental injury-induced pain in the mouse. Pain. 154(8):1358-67, 2013.
Heaivilin N, Gerbert B, Page JE, Gibbs JL. Public health surveillance of dental pain via Twitter. J. Dent. Res 90(9):1047-51, 2011.
Gibbs JL, Melnyk JL, and Basbaum AI. Differential TRPV1 and TRPV2 channel expression in dental pulp. J. Dent. Res. 90 (6): 765-70, 2011.
Gibbs JL, and Hargreaves KM. Neuropeptide Y Y1 Receptor Effects on Pulpal Nociceptors. J. Dent. Res. 87 (10): 948-52, 2008.
Gibbs JL, Diogenes A., Hargreaves KM. Neuropeptide Y modulates effects of bradykinin and prostaglandin E2 on trigeminal nociceptors via activation of Y1 and Y2 receptors. Br J Pharmacol 150 (1): 72-9, 2007.
Gibbs JL, Flores CM, Hargreaves KM. Attenuation of capsaicin-evoked mechanical allodynia by peripheral neuropeptide Y Y1 receptors. Pain 124: 167-74, 2006.
Gibbs JL, Flores CM, Hargreaves KM. Neuropeptide Y inhibits capsaicin-sensitive nociceptors via a Y1-receptor-mediated mechanism. Neuroscience 125:703-709, 2004.