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Faculty Information

Michael C. Alfano, DMD, PHP

Michael C. Alfano, DMD, PhD

Professor Emeritus
Basic Science and Craniofacial Biology



  • Certificate, Periodontics, Fairleigh Dickinson University School of Dentistry 1976
    PhD, Nutritional Biochemistry & Oral Biology, Massachusetts Inst. of Technology, Dept. of Nutrition & Food Science, 1971-1974
  • Trainee, Periodontics, Harvard University School of Dental Medicine, 1971-1973
  • DMD, University of Medicine & Dentistry of New Jersey 1971
  • BS, Biology, Rutgers University 1967

Research Interests / Professional Overview

  • Improving the Quality and Efficiency of Higher Education, especially Dental Education
  • Enhancing Oral and General Health through Better Therapy, Public Education, and Challenging the Dental Profession
  • Promotion of Improved Interactions Among Academic, Industrial and Government
  • Scientists, the Regulatory Agencies and the Public
  • Evaluation of New Products for the Personal Care, Dental, and Pharmaceutical Industries
  • Pathogenesis and Therapy of Periodontal Disease; Nutrition in Oral Health

Representative Publications

Complete listing available on the NYU Health Sciences Library site.

Search PubMed for articles.

Alfano, M.C.: "The Origin of Gingival Fluid" J. Theoretical Biol.47: 127-136, 1974

Alfano, M.C., Morhart, R., Metcalf, G. and Drummond, J.F.: "Presence of Collagenase from Clostridium Histolyticum in Gingival Sulcal Debris of a Primitive Population" J. Dent. Res. 53:142, 1974

Alfano, M.C.: "The Effect of Ascorbic Acid Deficiency on the Barrier Function of Guinea-
Pig Oral Mucosal Epithelium" Doctoral Thesis, 1974, Institute Archives, Massachusetts Institute of Technology Alfano, M.C., Drummond, J.F., and Miller, S.A.: "Technique for Studying the Dynamics of Oral Mucosal Permeability in Vitro" J. Dent. Res. 54: 194, 1975

Alfano, M.C., Miller, S.A., Drummond, J.F.: "Effect of Ascorbic Acid Deficiency on the Permeability and Collagen Biosynthesis of Oral Mucosal Epithelium" Ann. NY Acad. Sci. 258:253-263, 1975

Alfano, M.C., Drummond, J.F., and Miller, S.A.: "Localization of the Rate-Limiting Barrier to the Penetration of Endotoxin through Non-Keratinized Oral Mucosa In Vitro" J. Dent. Res. 54: 1180-1182, 1975

Inouye, L., Miller, S.A. and Alfano, M.C.: "The Lingual Ascorbic Acid Test: Lack of
Correlation with Blood and Tissue Levels of Ascorbic Acid in Guinea-Pigs" J. Dent
. 54:1143-1148, 1975

Alfano, M.C.: "The Role of the Host in Periodontal Disease" J.W. S. .Perio. 23:105-107, 1975

Alfano, M.C.: "Controversies, Perspectives and Clinical Implications of Nutrition in Periodontal Disease" Dent. Clin. North Amer. 20:519-548, 1976

DePaola, D.P. and Alfano, M.C.: "Tri-Phasic Nutritional Analysis" Dent. Clin. North Amer. 20: 613-633, 1976

Alfano, M.C., Kaslick, R.S., Chasens, A.I. and Brownstein, C.N.: "Passively Generated Increase in Human Gingival Crevicular Fluid Flow" J. Dent. Res. 55:1132, 1976

DePaola, D.P. and Alfano, M.C.: "Nutrition and Oral Health" Nutrition Today 12:6-32, 1977

Feingold, J., Chasens, A.I., Doyle, J.L. and Alfano, M.C.: "Preserved Scleral Allografts in Periodontal Defects in Man" J. Periodont. 48:4-12, 1977

Alfano, M.C., Chasens, A.I. and Masi, C.W.: "Autoradiographic Study of the Penetration of Radiolabelled Dextrans and Inulin through Non-Keratinized Oral Mucosa In Vitro" J. Periodont. Res. 12:368-377, 1977

Alfano, M.C.: "Prospective Improvements in the Prevention of Periodontal Disease" J. Prev. Dent. 5:26-29, 1978

Alfano, M.C., DePaola, D.P.: "Methods for Assessing Nutritional Status in Dental Practice" Quintessence Int. 9:115-125, 1978

Alfano, M.C.: "Effect of Acute Ascorbic Acid Deficiency on the DNA Content and Permeability of Guinea-Pig Oral Epithelium" Archs. Oral Biol. 23:929-932, 1978

Gillespie, B.R., Chasens, A.I., Brownstein, C.N. and Alfano, M.C.: "Relationship Between the Mobility of Human Teeth and Their Supracrestal Fiber Support" J. Perio. 50:120-124, 1979

Saroff, S., Alfano, M.C., Chasens, A.I. and King, W.: "Sonicated Passively Dispersed Hydrogen Peroxide in Periodontitis: Effects on Clinical Parameters and Myeloperoxidase Activity" J. Perio. Res. 15:216-222, 1980

Alfano, M.C.: "Nutrition, Sweeteners and Dental Caries" J. Food Tech. 34:70-74, 1980

Vogel, R.I., Deasy, M.J., Alfano, M.C. and Schneider, L.C.: "Effect of Folic Acid on Gingival Health in Women Taking Contraceptives" J. Prev. Dent. 6:221-227, 1980

Alfano, M.C.: "Diet and Nutrition in the Etiology and Prevention of Oral Disease" J. Dent. Res. 59:2194-2202, 1980

Alfano, M.C.: "Dental Caries: The Nature of the Problem" Cereal Foods 26:5-9, 1981

Vogel, R.I., Alfano, M.C. and Manhold, J.H.: "The Effect of Intrasulcular Brushing on Sulcular Epithelial Permeability" J. Periodont. 52:224-250, 1981

Alfano, M.C.: "Nutrition in Dental Practice: A Plea for Sanity" New York State Dent. J. 47:450-452, 1981

Ritchey, T.W., Lamster, I.B., Mann, P.H. and Alfano, M.C.: "The Effect of Zinc Chloride on the Development of Gingivitis in Beagle Dogs Treated with Cetylpyridinium Chloride" J.Dent. Res. 61:1217-1220, 1982

Lamster, I.B., Alfano, M.C., Seiger, M.C., Gordon, J.M.: "The Effect of Listerine Antiseptic on Reduction of Existing Plaque and Gingivitis" Clin. Prev. Dent. 5:12-16, 1983

Howell, T.H., Reddy, M.S., Li, K.L., Alfano, M.C., Weber, H.P., Kaplan, M.C., Vogel, R., Williams, R.C.: "Inhibition of Plaque Formation, Prevention and Treatment of Gingivitis with Sulfadiazines in Beagles" J. Dent. Res. 68 (Spec. Issue): 1712-1713, 1989

Howell, T.H., Reddy, M.S., Weber, H.P., Li, K.L., Alfano, M.C., Vogel, R., Tanner, A.C.R., Williams, R.C.: "Sulfadiazines Prevent Plaque Formation and Gingivitis in Beagles" J. Periodont. Res. 25:197-200, 1990

Howell, T.H., Reddy, M.S., Weber, H.P., Li, K.L., Alfano, M.C., Vogel, R., Tanner, A.C.R., and Williams, R.C.: "Sulfadiazines Reduce Gingivitis and Plaque Formation in Beagle Dogs" J. Clin. Periodontol. 17:734-737, 1990

Smith, M.A., Braswell, L.D., Collins, J.G., Boyd, D.L., Jeffcoat, M.K., Reddy, M., Li, K.L., Wilensky, S., Vogel, R., Alfano, M.C. and Offenbacher, S.: "Changes in Inflammatory Mediators in Experimental Periodontitis in the Rhesus Monkey" Infection and Immunity 61:1453-1459, 1993

Li, K.L., Vogel, R., Jeffcoat, M.K., Alfano, M.C., Smith, M.A., Collins, J.G.,
Offenbacher, S: "The Effects of Ketoprofen Creams on Periodontal Disease in Rhesus
Monkeys" J. Periodont. Res. 31:525-531, 1996

Khandwala, A., Van Inwegen, R.G., Alfano, M.C.: "5% Amlexanox Oral Paste A New Treatment for Recurrent Minor Aphthous Ulcers I. Clinical Demonstration of Acceleration of Healing and Resolution of Pain" Oral Surg Oral Med Oral Path Oral Radiol Endod 83:222-230, 1997

Khandwala, A., Van Inwegen, R.G., Charney, M.R. Alfano, M.C.: "5% Amlexanox Oral Paste A New Treatment for Recurrent Minor Aphthous Ulcers II. Pharmacokinetics and Demonstration of Clinical Safety" Oral Surg Oral Med Oral Path Oral Radiol Endod 83:231-238, 1997

Alfano, M.C.: "Dental Education: One Dean's Perspective" Journal Am College Dent. 68:8-12, 2002

Alfano, M.C.: "Titanium and Terrorism: The role of the implant dentist. Journal of ICOI (in press) 2003

Gordon, S.M., Heft, M.W., Dionne, R.A., Jeffcoat, M.K., Alfano, M.C., Valachovic, R.V., Lipton, J.A.: Capacity for Training in Clinical Research: Status and Opportunities J. Dent. Educ. 67:622-629, 2003

More, F.G., Phelan, J., Boylan, R., Glotzer, D., Psoter, W., Robbins, M., Rekow, E.D, Alfano, M.C.: "Predoctoral Dental School Curriculum for Catastrophe Preparedness" J. Dent. Ed. 68: 851-858, 2004.

Psoter, W.J., Alfano, M.C., Rekow, E.D.: "Meeting a Disaster's Medical Surge Demand"
CDA Journal 32: 694-700, 2004

Spielman, A.I., Fulmer, T., Eisenberg, E.S., Alfano, M.C.: "Dentistry, Nursing and Medicine: A Comparison of Core Competencies" J. Dent. Ed. 69: 1257-1271, 2005

Glotzer, D., More, F.G., Phelan, J., Boylan, R., Psoter, W.J., Robbins, M., Rekow, E.D., Godder, B., Alfano, M.C.: "Introducing a Senior Course on Catastrophe Preparedness into the Dental School Curriculum" J. Dent. Ed. (Submitted)

Petropoulis, V.C., Arbree, N.S., Tarnow, D., Rethman, M., Malmquist, J., Valachovic, R., Brunson, W.D., Alfano, M.C.: "Dean's American Dental Education Association Implant Workshop Survey" J. Dent. Ed. (Submitted)