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Bluestone Current Trials

White Spot Lesion Study

Clinical Study to Evaluate Experimental Mouth-rinse on White Spot Lesion Repair

The purpose of this research study is to detect changes on White Spot Lesions that occur after orthodontic treatment. The White Spot Lesions on the upper front teeth will be assessed for changes using an investigational mouth rinse.
Study Details

STUDY DETAILS

You may be eligible to participate in this study if you have one or more white spot lesions on the upper front teeth after removing your braces. You must be 10–65 years old and the braces must have been removed for a minimum of 30 days but no more than 90 days in order to qualify for this study.

The study will require 5 visits, over a 12-week period. We will monitor the changes during the entire length of the study using digital photographs and light measurements.

Interested in participating?

If you, a family member, or someone you know is interested in this study, please contact our clinical research coordinator Hanting Liang at (212) 992-7014 or hl2325@nyu.edu. Or, fill out our contact form. We will get back to you as soon as possible. Confidentiality will be maintained for all applicants and participants.

braces

Number of visits:

Duration:

Gender:

Ages:

Phone number:

Email address:

Status:

5

12 weeks

Male and Female

10–65 years old

(212) 992-7014

hl2325@nyu.edu

Currently recruiting


   

Mindfulness-Based Stress Reduction To Improve Cognitive Function During Aromatase Inhibitor Therapy

Improving Brain Health During Breast Cancer Therapy

Brief Description

If you are a postmenopausal woman who was diagnosed with breast cancer, you may qualify for this research study. The purpose of this study is to learn whether Mindfulness-Based Stress Reduction or a Health Enhancement Program improves cognitive function (your ability to concentrate and remember things) for women who take aromatase inhibitors. This study will evaluate cognitive function using a brain imaging technique called Magnetic Resonance Imaging (MRI), cognitive tests, and questionnaires. You will be paid up to $250 for completing the study.

Inclusion Criteria

  1. Have gone through menopause (are postmenopausal)
  2. Are younger than 80 years of age
  3. Are diagnosed with stage 0 (DCIS) or stage 1, 2, or 3 breast cancer
  4. Are taking an aromatase inhibitor or will be starting it soon

Exclusion Criteria

  1. No stage IV (metastatic) breast cancer
  2. Not claustrophobic (afraid of being in an MRI machine)
  3. No major psychiatric disorder (schizophrenia, bipolar I disorder); no neurological disorder (Parkinson's Disease, dementia); and no head trauma.

Interested in participating?

If you, a family member, or someone you know is interested in this study, please contact our clinical research coordinator Makeda Brown at 212-998-9202 or makeda.culley@nyu.edu. We will get back to you as soon as possible. Confidentiality will be maintained for all applicants and participants.

brain

Number of visits:

Duration:

Gender:

Ages:

Phone number:

Status:

11

6 months

Female

18–79 years

(212) 998-9310

Currently recruiting


   

Oral Cancer Biomarker Study

Do you have oral pre-cancer or cancer?

Seeking volunteers to take part in a study exploring the causes of oral cancer and oral cancer pain

Oral cancer presents a significant health problem. The 5-year survival rate for oral squamous cell carcinoma is 40% and is among the worst of all sites in the body. This survival rate has not improved over the past 40 years. Early detection and treatment profoundly impact survival; however there are currently no genetic markers available to identify pre-cancer and cancer.

The purpose of this study is to find what leads to cancer pain by examining the proteins in blood, saliva, urine, fluid, and tissue produced by oral cancer. This may help doctors to provide very specific therapy for oral cancer and pain. This study will compare the bio-fluids and tissues in oral cancer and oral pre-cancer patients, and healthy volunteers.

Study Details

You may be eligible to participate in this study if you have been recently diagnosed with a suspicious lesion in your mouth, are at least 18 years of age, not pregnant or lactating, and have never previously been treated for head or neck cancer with chemotherapy and/or radiation.

For patients diagnosed with oral cancer who are scheduled for surgery, this study consists of 3 visits over a period of 3 months.

For patients diagnosed with oral pre-cancer and are scheduled for tissue biopsy, this study consists of 2 visits over a period of 2 months.

This study is also recruiting healthy volunteers who are scheduled for teeth extraction or corrective jaw surgery at the NYU College of Dentistry. For this group of participants, this study consists of 1 visit, which will take place at the same time as your scheduled visit to the dental clinic.

Interested in participating?

If you, a family member, or someone you know is interested in this study, please contact our clinical research coordinator at the Bluestone Center at 212-998-9310. We will get back to you as soon as possible. Confidentiality will be maintained for all applicants and participants.

oral cancer biomarker study

Number of visits:

Start date:

Duration:

Gender:

Ages:

Phone number:

Status:

1–3 days

2/1/2001

1 day to 3 months

Male and Female

18 and over

(212) 998-9310

Currently recruiting