Faculty Information
Yalda Moayedi, PhD
Assistant Professor
Molecular Pathobiology
433 1st Avenue, NY 10010
ym2994@nyu.edu
Phone: 212-998-9708
Visit the Moayedi Lab website >>>
Education
- Ph.D., Neuroscience Graduate Program, Baylor College of Medicine, Houston, Texas, 2013
- B.S., Neurobiology, University of Texas, Austin, Texas, 2004
- B.A., Middle Eastern Studies, University of Texas, Austin, Texas, 2004
Honors/Credentials
Kavli Fellow, National Academy of Sciences, 2023
AChemS Polak Young Investigator Award, 2021
Research Interests/Professional Overview
The primary research interest of the Moayedi laboratory is to understand the somatosensory neurons that innervate the oral cavity and upper airway, and how they contribute to oral functions including as flavor perception, food choice, feeding mechanics, airway defense, and speech. While it is well recognized that somatosensation is an important contributor to these daily tasks, little is known about the neurons and circuits that underlie them. Understanding this fundamental biology has far-reaching implications for developing new treatments for diseases of orofacial neurons including dysphagia, dysphonia, and cranial neuropathies. Her lab uses a combination of molecular biology, histology, physiology, functional imaging, and behavior to address these gaps in knowledge.
Current Funding
R21 DC018898: Mechanosensory substrates of flavor in the mammalian tongue
Representative Publications
Pennington-FitzGerald, W., A. Joshi, E. Honzel, I. Hernández-Morato, M.J. Pitman, Y. Moayedi. Development and Application of Automated Vocal Fold Tracking Software in a Rat Surgical Model. Laryngoscope. (2023) Aug 6. doi: 10.1002/lary.30930. Epub ahead of print. PMID: 37543969.
Moayedi Y., S. Xu, S.K. Obayashi, B.U. Hoffman, G.J. Gerling, E.A. Lumpkin. The cellular basis of mechanosensation in mammalian tongue. Cell Reports. (2023) Feb 9; 42(2):112087; doi: 10.1016/j.celrep.2023.112087.
Moayedi Y*., S. Michlig, M. Park, A. Koch, E.A. Lumpkin. Localization of TRP channels in healthy oral mucosa from human donors. eNeuro (2022) Dec 6. 0328-21.2022; DOI:10.1523/ENEURO.0328-21.2022. *Corresponding author.
Cole C.L., V.X. Yu, S. Perry, A. Seenauth, E.A. Lumpkin, M.S. Troche, M.J. Pitman, Y. Moayedi. Healthy Human Adult Laryngopharyngeal Sensory Innervation Density Correlates with Age. The Laryngoscope (2022) Jul 16. doi: 10.1002/lary.30287. Online ahead of print.
Moayedi Y*., S. Michlig, M. Park, A. Koch, E.A. Lumpkin*. Somatosensory innervation of healthy human oral tissues. J Comp Neurol (2021) Aug 1;529(11):3046-3061. doi: 10.1002/cne.25148. *Co-corresponding/Joint-senior author.
Moayedi, Y., S. Greenberg, B. A. Jenkins, K. L. Marshall, D. M. Owens and E. A. Lumpkin. Camphor oil induces tumor regression through cytotoxic T cell-dependent mechanisms. Mol Carcinog (2019) May;58(5):722-734. doi: 10.1002/mc.22965.
Moayedi, Y., L. Duenas-Bianchi and E. A. Lumpkin. Somatosensory innervation of the oral mucosa of adult and aging mice. Scientific Reports. (2018) 8(1):9975.
Moayedi Y, M.L. Basch, N.L. Pacheco, S.S. Gao, R. Wang, W. Harrison, N. Xiao, J.S. Oghalai, P.A. Overbeek, G. Mardon¶, and A.K. Groves¶. The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs. PLoS Genet. (2014) 10(1).