Selected Publications

  1. Amodeo GF, Lee BY, Krilyuk N, Filice CT, Valyuk D, Otzen DE, Noskov S, Leonenko Z, Pavlov EV. C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition. Sci Rep. 2021 Apr 22;11(1):8744.
  2. Solesio ME, Xie L, McIntyre B, Ellenberger M, Mitaishvili E, Bhadra-Lobo S, Bettcher LF, Bazil JN, Raftery D, Jakob U, Pavlov EV. Depletion of mitochondrial inorganic polyphosphate (polyP) in mammalian cells causes metabolic shift from oxidative phosphorylation to glycolysis. Biochem J. 2021 Apr 30;478(8):1631-1646.
  3. Neginskaya MA, Strubbe JO, Amodeo GF, West BA, Yakar S, Bazil JN, Pavlov EV. The very low number of calcium-induced permeability transition pores in the single mitochondrion. J Gen Physiol. 2020; Oct 5;152(10):e202012631. 
  4. Neginskaya MA, Solesio ME, Berezhnaya EV, Amodeo GF, Mnatsakanyan N, Jonas EA, Pavlov EV. ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore. Cell Reports 2019 Jan 2;26(1):11-17.e2. PMID: 30605668
  5. Elustondo PA, Nichols M, Negoda A, Thirumaran A, Zakharian E, Robertson GS, Pavlov EV. Mitochondrial permeability transition pore induction is linked to formation of the complex of ATPase C-subunit, polyhydroxybutyrate and inorganic polyphosphate. Cell Death Discov. 2016 Dec 5;2:16070. doi: 10.1038/cddiscovery.2016.70. PMID: 27924223
  6. Abramov AY, Fraley C, Diao CT, Winkfein R, Colicos M, Duchen MR, French RJ, Pavlov E. Targeted polyphosphatase expression alters mitochondrial metabolism and inhibits calcium-dependent cell death. Proc Natl Acad Sci U S A, Nov; 104 (46): 18091-18096. 2007. PMID: 17986607
  7. Pavlov E, Zakharian E, Bladen C, Diao CTM, Grimbly C, Reusch RN, French RJ. A large, voltage-dependent channel, isolated from mitochondria by water-free chloroform extraction. Biophys. J. Apr; 88(4): 2614-2625. 2005. PMID: 15695627
  8. Both ANT and ATPase are essential for mitochondrial permeability transition but not depolarization. MA Neginskaya, SE Morris, EV Pavlov. IScience 25 (11)


Recent Publications