Research Focus
The Schmidt lab investigates neurobiological mechanisms that are responsible for oral cancer pain. The group developed and validated the University of California San Francisco Oral Pain Questionnaire to quantify trigeminal pain/dysfunction in patients, and invented a device and operant assay to quantify a behavioral index of orofacial nociception/dysfunction in preclinical models of oral cancer. Projects address mediators responsible for pain in oral cancer patients, and study preclinical models to define responsible peripheral nociceptive mechanisms.
Publications
Complete listing available on the NYU Health Sciences Library site.
Active Projects
W81XWH-22-1-0239 (Bunnett/Schmidt)
09/01/2022 – 08/31/2025
DoD
Receptors in Endosomes Mediate Chronic Pain Associated with Trauma, Inflammation, and Stress: Non-Opioid Targets for Sustained Relief of Pain
R01DE029951 (Bunnett/Schmidt)
09/15/2020 – 08/31/2024
NIH/NIDCR
Targeting Endosomal Receptors for Treatment of Chronic Pain
R01DE029951-01S1 (Bunnett/Schmidt)
09/01/2021 – 08/31/2024
NIH/NIDCR
Targeting Endosomal Receptors for Treatment of Chronic Pain - Admin Supplement 1
R01DE029951-01S2 (Bunnett/Schmidt)
09/01/2022 – 08/31/2023
NIH/NIDCR
Targeting Endosomal Receptors for Treatment of Chronic Pain - Admin Supplement 2
R01CA231396 (Albertson/Schmidt)
03/01/2021 – 02/28/2026
NIH/NCI
TRPV1 nociceptors in oral carcinogenesis and pain
R01DE029694 (Schmidt/Yamano)
01/08/2021 –12/31/2025
NIH/NIDCR
Intratumor co-delivery of DNA and RNA to relieve cancer pain
R01CA228525 (Albertson/Schmidt)
09/01/2019 – 08/31/2024
NIH/NCI
Artemin overexpression in oral cancer pain and carcinogenesis
R01DK118971 (Bunnett/Schmidt)
09/01/2018 – 05/31/2023
NIH/NIDDK
Trafficking-Dependent Signaling of Pain by Protease-Activated Receptors
R01DE026806 (Schmidt/Bunnett)
01/01/2018 – 12/31/2022
NIH/NIDCR
Protease/PAR2/TRPV4 Axis and Oral Cancer Pain
R01DE026806-02S1 (Schmidt/Bunnett)
09/20/2019 – 12/31/2022
NIH/NIDCR
Protease/PAR2/TRPV4 Axis and Oral Cancer Pain - Admin Supplement