Research Focus

The Schmidt lab investigates neurobiological mechanisms that are responsible for oral cancer pain. The group developed and validated the University of California San Francisco Oral Pain Questionnaire to quantify trigeminal pain/dysfunction in patients, and invented a device and operant assay to quantify a behavioral index of orofacial nociception/dysfunction in preclinical models of oral cancer. Projects address mediators responsible for pain in oral cancer patients, and study preclinical models to define responsible peripheral nociceptive mechanisms.

Publications

Complete listing available on the NYU Health Sciences Library site.

Active Projects

W81XWH-22-1-0239 (Bunnett/Schmidt)
09/01/2022 – 08/31/2025
DoD

Receptors in Endosomes Mediate Chronic Pain Associated with Trauma, Inflammation, and Stress: Non-Opioid Targets for Sustained Relief of Pain
 

R01DE029951 (Bunnett/Schmidt)
09/15/2020 – 08/31/2024
NIH/NIDCR

Targeting Endosomal Receptors for Treatment of Chronic Pain
 

R01DE029951-01S1 (Bunnett/Schmidt)
09/01/2021 – 08/31/2024
NIH/NIDCR

Targeting Endosomal Receptors for Treatment of Chronic Pain - Admin Supplement 1

 

R01DE029951-01S2 (Bunnett/Schmidt)
09/01/2022 – 08/31/2023
NIH/NIDCR

Targeting Endosomal Receptors for Treatment of Chronic Pain - Admin Supplement 2

 

R01CA231396 (Albertson/Schmidt)
03/01/2021 – 02/28/2026
NIH/NCI

TRPV1 nociceptors in oral carcinogenesis and pain

R01DE029694 (Schmidt/Yamano)
01/08/2021 –12/31/2025
NIH/NIDCR

Intratumor co-delivery of DNA and RNA to relieve cancer pain
 

R01CA228525 (Albertson/Schmidt)
09/01/2019 – 08/31/2024
NIH/NCI

Artemin overexpression in oral cancer pain and carcinogenesis
 

R01DK118971 (Bunnett/Schmidt)
09/01/2018 – 05/31/2023
NIH/NIDDK

Trafficking-Dependent Signaling of Pain by Protease-Activated Receptors
 

R01DE026806 (Schmidt/Bunnett)
01/01/2018 – 12/31/2022
NIH/NIDCR

Protease/PAR2/TRPV4 Axis and Oral Cancer Pain
 

R01DE026806-02S1 (Schmidt/Bunnett)
09/20/2019 – 12/31/2022
NIH/NIDCR

Protease/PAR2/TRPV4 Axis and Oral Cancer Pain - Admin Supplement