Faculty Information

Edwin Rosado-Olivieri, PhD

Assistant Professor
Department of Molecular Pathobiology
433 1st Avenue, Room 704
New York, NY 10010
Phone (office): 212-998-9637 (extension 89637)
Email: er3400@nyu.edu

 

Visit the Rosado-Olivieri Lab website >>>

 

Education

Postdoctoral Fellowship, Laboratory of Synthetic Embryology, The Rockefeller University in New York, NY, 2023

Ph.D. in Developmental and Regenerative Biology, Department of Stem Cell and Regenerative Biology, Harvard University in Cambridge, MA, 2019

B.Sc., Cellular and Molecular Biology (Summa cum laude), University of Puerto Rico, Rio Piedras in San Juan, PR, 2014

Honors and Credentials

  • Robertson Therapeutic Development Fund Commercialization Award (2021)
  • Merit Award, International Society for Stem Cell Research (2019)
  • Blavatnik Biomedical Accelerator (2019)
  • Harvard Distinction in Teaching Award (2016)
  • National Science Foundation Graduate Research Fellowship (2014-2019)
  • Distinction in Research Award, University of Puerto Rico (2015)
  • Research and Creativity Award, University of Puerto Rico (2015)
  • MARC (NIGMS) Fellowship (2012-2014)
  • RISE (NIH) Fellowship (2011-2012)
  • Amgen Scholar, University of California San Francisco (2013)

Research Interests

Edwin Rosado-Olivieri is a stem cell, developmental and regenerative biologist, studying the mechanisms that choreograph human organ development and function. In humans, how developing organs coordinate tissue morphogenesis and cellular differentiation remains poorly understood. Edwin’s laboratory seeks to unravel the cellular and molecular underpinnings of human organogenesis. Their research focuses on the development of stem cell-based models, computational, and genetic approaches to uncover fundamental aspects of human development and disease. They specialize in the development of innovative stem cell-based mini-organ models and high-throughput quantitative paradigms to explore and understand the complexities of human organ development. Edwin’s goal is to use their research to shed light on how these processes are dysregulated in human diseases, ultimately leading to more effective treatments and better outcomes for patients. Their approach provides an innovative and quantitative framework for interrogating fundamental aspects of human embryology, which will ultimately enhance the in vitro derivation of human cells for disease modeling and clinical applications.

Current Funding

New York University

Representative Publications

Rosado-Olivieri E.A., Razooky B., Le Pen, J., De Santis, R., Barrows, D., Sabry, Z.1, Hoffmann, H.-H., Park, J., Carroll, T.S., Poirier, J.T., Rice, C.M., Brivanlou, A.H. (2023) Organotypic Human Lung Bud Microarrays Identify BMP-dependent SARS-CoV-2 Infection in Lung Cells. Stem Cell Reports S2213-6711(23)00103-0.

Rosado-Olivieri E.A., Aigha I., Kenty, JH, Melton DA (2020) Identification of a LIF-responsive replication-competent subpopulation of human beta cells. Cell Metabolism 31, 327-338.e6.

a.  Selected as Landmark Article in Stem Cells by Cell Metabolism.

Rosado-Olivieri E.A., Anderson K, Kenty JH, Melton DA (2019) YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells. Nature Communications 10, 1464.

De Santis, R., Rice, E., Croft, G., Yang, M., Rosado-Olivieri, E.A., Brivanlou, A.H. (2024) The Emergence of Human Gastrulation Upon in vitro Attachment. Stem Cell Reports 19, 1-13.

Jordan, R., Ford-Scheimer, S.L., Alarcon, R.M., Atala, A., Borenstein, J.T., Brimacombe, K.R., Cherry, S.R., Clevers, H., Davis, M.I., Funnell, S.G., Gehrke, L., Griffith, L.G., Grossman, A.C., Hartung, T., Ingber, D.E., Kleinstreuer, N.C., Kuo, C.J., Lee, E.M., Mummery, C.L., Pickett, T.E., Ramani, S., Rosado-Olivieri, E.A., Rutter, J.L., Struble, E.V., Wan, Z., Williams, W.S., Hall, M.D., Ferrer, M., Markossian, S. (2023) Report of the Assay Guidance Workshop on 3D Tissue Models for Antiviral Drug Development. Journal of Infectious Diseases, jiad334.

Rosado-Olivieri E.A., Razooky B., Hoffmann H.-H., De Santis R.,  Rice C.M.,  Brivanlou, A.H (2021) Self-organized stem cell-derived human lung buds with proximo-distal patterning and novel targets of SARS-CoV-2. bioRxiv DOI: https://doi.org/10.1101/2021.01.06.425622

R De Santis, F Etoc, EA Rosado-Olivieri, AH Brivanlou. (2021) Self-organization of human dorsal-ventral forebrain structures by light induced SHH. Nature Communications 12 (1), 1-11

Rosado-Olivieri E.A, Brivanlou, A.H. (2021) Synthetic by design: Exploiting tissue self-organization to explore early human embryology. Developmental Biology, DOI: https://doi.org/10.1016/j.ydbio.2021.01.004.

Rosado-Olivieri E.A, Brivanlou, A.H. (2020) Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures. Cell Stem Cell 26, 467-468.